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| Antigenic Specificity | BACE1 |
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| Clone | MM0105-6J26 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB, IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-BACE1 Recombinant Antibody (MM0105-6J26). This product is a mouse antibody that recognizes BACE1. The antibody MM0105-6J26 can be used for immunoassay techniques such as: WB, IHC-P. This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. Vassar et al. (1999) found that transient overexpression of BACE did not affect APP expression, but decreased alpha-secretase cleavage and increased beta-secretase activity in cells expressing wildtype or Swedish mutant (104760.0008) APP. BACE overexpression induced cleavage only at the known beta-secret |
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| Immunogen | Human recombinant fragment-extracellular domain |
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| Other Names | Beta-Site APP-Cleaving Enzyme 1; Membrane-Associated Aspartic Protease 2; Beta-Site APP Cleaving Enzyme 1; Aspartyl Protease 2; EC 3.4.23.46; Memapsin-2; Asp 2; BACE; ASP2; Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme; Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1; Transmembrane Aspartic Proteinase Asp2; Beta-Secretase 1 Precursor Variant 1; Beta-Site APP-Cleaving Enzyme; APP Beta-Secretase; EC 3.4.23; KIAA1149; HSPC104 |
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| Gene, Accession # | Gene ID: 23621, UniProt: P56817 |
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| Catalog # | CBMAB-0114CQ |
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| Price | |
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| Order / More Info | BACE1 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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