GLUT 2, Rat (Glucose Transporter, Insulin Regulatable) (Control Peptide)
Description
Highly purified. Control Peptide for G3900-15D (affinity purified antibody) and G3900-15 (antiserum). G3900-15F is 16 amino acid peptide sequence corresponding to the exoplasmic loop between helices 1 and 2 of rat liver Glucose Transporter. Rat GT21 peptide sequence has 93% identity with mouse and human Glut-2 (15/16 AA). Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (Glut-1 to Glut-7, 40-60kD) and sodium glucose co-transporter-1 (SGLT-1, 662 amino acids; ~75kD). Individual member of this family have identical predicted secondary structures with 12 transmembrane domains. Both N and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting. Glut isoforms differ in their tissue expressi