Purity >95%. m -3M3FBS is an activator of phospholipase C (PLC) that stimulates superoxide generation, increase in cytoplasmic calcium, and inositol phosphate formation in human neutrophils when used at a concentration of 15-50 μM. It stimulates cytoplasmic calcium increases in several cell lines and, at 25 μM in vitro, promotes the hydrolysis of phosphatidylinositol bisphosphate by all PLC isoforms. m -3M3FBS is used to study PLC signaling in cells and animals, often in conjunction with the PLC inhibitor U-73122 .