Purity >95%. PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 μM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells.
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Other Names
L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl-L-glutamic acid, Arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid, Protein Kinase G Inhibitor