Probetacellulin, cleaved to Betacellulin, active (BTC), Recombinant, Human
Description
Purity ≥98% as determined by SDS-PAGE and HPLC. Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. (ECO:0000269|PubMed:8570211). Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 0.05ng/ml, corresponding to a specific activity of 2.0x10e7 IU/mg.