Purity >98%. CFTR Inhibitor II, or GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 μM). GlyH-101 binds to a site at the external pore of CFTR, occluding the pore and rapidly preventing chloride transport.
Size
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Applications
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Other Names
2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide N-2-naphthalenyl-glycine, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II, GlyH-101