MDS1, Recombinant, Human, aa1-169, His-Tag (Myelodysplasia Syndrome Protein 1)
Description
Purity ~85% (SDS-PAGE). MDS1 is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. Source: Recombinant protein corresponding to aa1-169 from human MDS1, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~21.1kD (192aa) Applications: Suitable for use in SDS-PAGE.