Recombinant Drosophila melanogaster Stress-activated protein kinase JNK (bsk)
Description
Purity > 90% as determined by SDS-PAGE. MW: 47kDa. Full Length: 1-372aa. N-terminal 6xHis-tagged. Drosophila melanogaster (Fruit fly). Responds to activation by environmental stress by phosphorylating a number of transcription factors, primarily components of AP-1 such as Jra and also the transcriptional repressor aop, and thus regulates transcriptional activity. Component of the immune response activated by bacterial infection, and is involved in wound healing and in dorsal closure, a morphogenetic movement during embryogenesis. Controls the expression of a phosphatase, puckered, at the edges of wounded epidermal tissue and in the dorsal epithelium during dorsal closure.