An RXR agonist (Kd = 3 nM); selective for RXRs over RARs (Kd = >10,000); induces apoptosis in HL-60 human leukemia cells when used at a concentration of 1 μM in combination with TTNPB; dose-dependently inhibits COX-2 expression (100, 300 and 1000 nM) and increases ABCA1 levels in macrophage-like RAW 264.7 cells; inhibits vinyl carbamate-induced lung tumor growth in mice (40 mg/kg)