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Description
ANPEP / CD13 Antibody (clone ER-BMDM1) LS-C96362. The antigen is a 160kDa membrane associated protein which shows aminopeptidase N activity. It is homologous to the human CD13 marker. Antigen distribution: Isolated Cells: The antigen is present on the majority of isolated dendritic cells of the spleen and lymph node. Over 80% of thioglycollate elicited peritoneal exudate macrophages also express the ER-BMDM1 related antigen. It is absent from freshly isolated bone marrow cells and blood cells. Tissue Sections: Lymphoid organs: macrophages surrounding small blood vessels, interdigitating cells, subpopulation of macrophages in the T-cell areas, capsular and medullary cord macrophages in lymph nodes. Non-lymphoid organs: subpopulation of macrophages (mainly in connective tissues) and dendrocytes, structures positive for aminopeptidase such as the brush border of the small intestine, bile canaliculi in the liver and tubuli and glomeruli in the kidney or type II pneumocytes in the lung. Kupffer cells are negative. Specificity: Mouse: Mature macrophages. Other species: not tested.
Immunogen
Cultured monocytes, day 7
Other Names
ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1