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Description
Rabbit IgG polyclonal antibody for Krueppel-like factor 4(KLF4) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. Kruppel-like factor 4, also known as EZF or GKLF, is a protein that in humans is encoded by the KLF4 gene. This gene is mapped to 9q31.2. KLF4 gene encodes a member of the Kruppel family of transcription factors. This gene plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. This gene involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human KLF4(93-108aa RRETEEFNDLLDLDFI), identical to the related mouse and rat sequences.
Other Names
Krueppel-like factor 4;Epithelial zinc finger protein EZF;Gut-enriched krueppel-like factor;KLF4;EZF, GKLF;