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Description
Zinc finger proteins have regions (zinc finger domains) consisting of cysteines and histidines or cysteines alone which can form a tetrahedral complex around a Zinc ion. Zinc finger represent a class of DNA-binding proteins, act as transcriptional regulators of other genes. These multifunctional transcription factors exhibits control on a large number of cellular genes by binding to sites overlapping the transcription start site and plays an important role in development and differentiation. Hromas et al. in an effort to identify activators of the genetic cascade in hemopoietic differentiation probed a human myeloid cDNA library. ZNF42 may be a regulator of transcriptional events during hemopoietic development. This Rex1 (ZFP42) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Rex1 (ZFP42).
Immunogen
Human Rex1.
Other Names
REX1; ZFP42; ZNF754; Zinc finger protein 42 homolog; Reduced expression protein 1; Zinc finger protein 754