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Description
CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Synonyms: Polyclonal CHRNA4 antibody, Anti-CHRNA4 antibody, cholinergic receptor, nicotinic, alpha 4 antibody, BFNC antibody, EBN antibody, EBN1 antibody, NACRA4 antibody.
Immunogen
CHRNA4 antibody was raised in rabbit using the N terminal of CHRNA4 as the immunogen