Recombinant Human Nuclear inhibitor of protein phosphatase 1 (PPP1R8)
Description
Purity > 90% as determined by SDS-PAGE. MW: 52.1kDa. Full Length of Isoform 2: 1-209aa. N-terminal GST-tagged. Homo sapiens (Human). Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Protein phosphatase 1 regulatory inhibitor subunit 8