MIA-2, Recombinant, Human (Melanoma Inhibitory Activity Protein 2, FLJ22404)
Description
Purity ~98% (SDS-PAGE and HPLC). MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3)-like domain. MIA2 is predominantly expressed in hepatocytes. Elevated levels of MIA2 may represent a clinically useful marker for diagnosis of hepatic disease activity and severity. Recombinant human MIA-2 is a 101aa, 11.5kD protein comprising the MIA homologous N-terminal region of the full length MIA-2 protein. Source: Recombinant protein corresponding to human MIA-2, expressed in E.coli. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L