bovine, hamster, human, mouse, nonhuman primate, rat
Isotype
IgG
Format
purified
Size
100 μL
Concentration
n/a
Applications
Immunoprecipitation: 1:50, Western Blot: 1:1000
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
N-WASP Monoclonal Antibody (C.427.3). The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues.
Immunogen
n/a
Other Names
Wiskott-Aldrich syndrome gene-like; neural Wiskott-Aldrich syndrome protein