DNA was prepared from cell line WM3622. WM3622 is a metastatic human melanoma cell line that display large flat cell morphology. This cell line contains a F337S mutation in the PTEN gene. The codon for phe337 is replaced with a serine residue and this substitution could be highly detrimental to catalysis by PTEN and to its conformational stability. WM3622 cells produce xenograft tumors when injected into immunocompromised mice.
Size
10 μg
Concentration
200 ng / μl
Applications
Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis.
Other Names
Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft