A neuropeptide with diverse biological activities; binds to GRPR in rat pancreatic acinar cells (Ki = 1.88 nM) and to frog BB4 in CHO cells overexpressing the receptor (Ki = 1.7 nM); increases blood glucose, free fatty acids, and corticosterone levels in rats (100 ng per animal); decreases food intake by food-deprived or insulin pretreated rats (50 ng per animal); delays gastric emptying in rats by 55.8% (16 μg/kg, i.p.); inhibits gastric secretion (500 ng per animal)