Purity ~80% (SDS-PAGE). Fucosyltransferase 3, also known as FUT3, may catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. This protein may be involved in blood group Lewis determination; Lewis-positive (Le+) individuals have an active enzyme while Lewis-negative (Le-) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links. Source: Recombinant protein corresponding to aa35-361 from human FUT3, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~40.6kD (350aa) AA