Potent hepatoselective glucokinase activator (EC50 = 90 nM). Exhibits >50-fold liver to pancreas ratio of tissue distribution. Reduces fasting and postprandial glucose levels with no hypoglycemia in a rat diabetes model. Purity 98%. MW (observed): 396.36
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
6-[[(2S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid. EC 2.7.1, EC 2.7.1.2, FGQTL3, GCK, GK, GLK, glucokinase (hexokinase 4), hexokinase-4, Hexokinase-D, HHF3, HK4, HK4pancreatic isozyme, HKIV, HXKP, LGLK, maturity onset diabetes of the young 2, MODY2