PDRG1, aa1-133, Recombinant, Human (p53 and DNA-damage Regulated 1, C20orf126, PDRG)
Description
Purity ~90% (SDS-PAGE). PDRG1, also known as PDRG or C20orf126, is a 133aa protein that localizes to the cytoplasm and belongs to the prefoldin subunit b family. Expressed predominately in normal testicular tissue, PDRG1 is functionally induced by ultraviolet light and is thought to play a role in chaperone-mediated protein folding, possibly playing a role in cellular degradation. It is associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Source: Recombinant corresponding to aa1-133 of human PDRG1 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG Molecular Weight: 17.6kD (153aa) confirmed by MALDI-TOF