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Description
Rabbit Anti-Egln1 Recombinant Antibody (D31E11). Provided herein is a Rabbit monoclonal antibody against Human Egl-9 Family Hypoxia Inducible Factor 1. The antibody can be used for immunoassay techniques, such as WB, IP. Egln1 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis fa
Immunogen
n/a
Other Names
Egl-9 Family Hypoxia Inducible Factor 1; Prolyl Hydroxylase Domain-Containing Protein 2; Hypoxia-Inducible Factor Prolyl Hydroxylase 2; HIF-Prolyl Hydroxylase 2; C1orf12; HIF-PH2; HPH-2; PHD2; Zinc Finger MYND Domain-Containing Protein 6; Egl-9 Family Hypoxia-Inducible Factor 1; Egl Nine Homolog 1 (C. Elegans); EGL Nine (C.Elegans) Homolog 1; HIF Prolyl Hydroxylase 2;