Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT . Canopy 3 homolog, also known as CNPY3, is Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. This protein is required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, CNPY3i s required for both innate and adaptive immune responses. Recombinant human CNPY3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.