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Description
CBX2 Monoclonal Antibody. This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Immunogen
n/a
Other Names
CDCA6, M33, SRXY5, Pc class homolog, cell division cycle associated 6, chromobox homolog 2 (Pc class homolog, Drosophila), chromobox protein homolog 2, modifier 3