A cell-permeable non-steroidal antagonist of GPER, inhibiting activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively); has no detectable binding activity to either ERα or ERβ
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
receptors antagonists steroids endocrinology biochemistry cancers diabetes bone-related research bones related G proteins coupled estrogens GPR30 GPR-30 GPRs 30 GPERs cell-permeable cells permeables non-steroidal nonsteroidal non steroidal 17β-estradiol 17beta-estradiol 17.beta.-estradiol 17b-estradiol estradiol G1 G-1 Gs 1 36 G36 ERs Erα ERβ ERalpha ERbeta ER.alpha. ER.beta. Era ERb ERKs EGFs