Recombinant Human Hermansky-Pudlak syndrome 1 protein (HPS1)
Description
Purity > 90% as determined by SDS-PAGE. MW: 63.5kDa. Full Length of Isoform III: 1-324aa. N-terminal GST-tagged. Homo sapiens (Human). Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38