Purity ≥95% (SDS-PAGE). PINX1(PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. This protein contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1. PINX1 has been shown to be a potent telomerase inhibitor and putative tumor suppressor. Source: Recombinant human PINX1, fused to His-tag at N-terminus, was expressed in E.coli. Molecular Weight: 39.1kD (348aa) Sequence of amino acids: MGSSHHHHHH SSGLVPRGSH MSMLAERRRK QKWAVDPQNT AWSNDDSKFG QRMLEKMGWS KGKGLGAQEH GATDHIKVQV KNNHLGLGAT INNEDNWIAH QDDFNQLLAE LNTCHGQETT DSSDKKEKKS FSLEEKSKIS KNRVHYMKFT KGKDLSSRSK TDLDCIFGKR QSKKTPEGDA SPSTPEENET TTTSAFTIQE YFAKRMAALK NKPQVPVPGS DISETQVERK RGKKINKEAT GKDVESYLQP KAKRHTEGKP ERAEAQERVA KKKSAPAEEQ LRGPCWDQSS KASAQDAGDH VQPPEGRDFT LKPKKRRGKK KLQKPVEIAE DATLEETLVK KKKKKDSK Endotoxin Level: ≤1EU/ug
Size
100ug
Concentration
n/a
Applications
n/a
Other Names
PINX1, 1-328aa, Recombinant, Human (67-11-3 Protein, Hepatocellular Carcinoma-related Putative Tumor Suppressor, LPTL, LPTS, PIN2 Interacting Protein 1)