Purity ~90% (SDS-PAGE). Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Source: Recombinant protein corresponding to aa19-170 from human PGF, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~30.7kD AA