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Description
Function: May be involved in neuronal migration.Subcellular location: SecretedTissue specificity: Expressed in heart and brain. Present in brain (at protein level). In adult brain, found almost exclusively in areas of secondary neurogenesis from the hippocampus and the subventricular zone.Subcellular location: Cytoplasm ?? cytoskeleton. Note: Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones. Also known as: NAV1, Steerin-1, STEERIN1, Pore membrane and/or filament-interacting-like protein 3, Unc-53 homolog 1, UNC53H1.
Immunogen
A synthetic peptide from aa region 930-964 of human Neuron navigator 1 (NAV1, Steerin-1) conjugated to an immunogenic carrier protein was used as the antigen.