NT-3 is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, Mouse and rat NT-3 are identical. Alternative Names: NGF-2 protein, HGNF protein, NT-3 protein, Neurotrophic factor protein, NT 3, Neurotrophin-3 protein, NT 3 protein, Nerve growth factor-2 protein, NT-3 protein, NT3, NT-3