Recombinant Human DNA nucleotidylexotransferase (DNTT)
Description
Purity > 90% as determined by SDS-PAGE. MW: 62.5kDa. Full Length: 1-509aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Tplate-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.