Recombinant Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (TAB2), partial
Description
Purity > 85% as determined by SDS-PAGE. MW: 37.1kDa. Partial: 401-693aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2) (KIAA0733) (MAP3K7IP2)