Fibroblast Growth Factor Receptor 3 (FGFR3) protein (Fc Tag)
Description
Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorigenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1 to -4 are known. Alternative Names: Fibroblast Growth Factor Receptor 3 protein, FGFR-3 protein (Fc Chimera)