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Description
Purified anti-Abi-1. ABI1, also known as Abelson interactor 1, interacts with the nonreceptor tyrosine kinases ABL1 and/or ABL2 to negatively regulate cell growth and transformation. It is also involved in Ras to Rac signal transduction, cytoskeletal reorganization, and EGFR signaling.
Immunogen
This antibody was developed against recombinant Abi-1 (human spectrin SH3 domain binding protein 1).
Other Names
Abl interactor 1, Abelson interactor 1, nap1 binding protein, abl-binding protein 4, interactor protein AblBP4, Abl-interactor protein 1 long, eps8 SH3 domain-binding protein, spectrin SH3 domain-binding protein 1, Spectrin Binding Protein,SIG-39710-200