KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli. MW: 19.2 kDa (168 aa, 73-216 aa + His Tag), confirmed by MALDI-TOF. Purity ≥90%
Size
100 μg
Concentration
0.5 mg/ml
Applications
RUO
Other Names
NKG2-D type II integral membrane protein, CD314, D12S2489E, KLR, NKG2-D, NKG2D