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Description
Monoclonal antibody to detect Adipophilin in human samples. Adipophilin belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
Immunogen
Recombinant human Adipophilin protein fragment (aa 249-376)
Other Names
Adipophilin, ADFP, Adipose differentiation-related protein (ADRP), Perilipin-2 (PLIN2)