If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family B member 6, mitochondrial(ABCB6) detection. Tested with WB, IHC-P, ICC in Human. No cross reactivity with other proteins. ABCB6, ATP-binding cassette sub-family B member 6, mitochondrialis a protein that in humans is encoded by the ABCB6 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB6(818-842aa YADMWQLQQGQEETSEDTKPQTMER).
Other Names
ATP-binding cassette sub-family B member 6, mitochondrial;Mitochondrial ABC transporter 3;Mt-ABC transporter 3;P-glycoprotein-related protein;Ubiquitously-expressed mammalian ABC half transporter;ABCB6;MTABC3, PRP, UMAT;