A Mas receptor antagonist (IC50 = 0.3 nM); prevents the antidiuretic effects of Ang (1-7) in water-loaded rats (0.01 mg/kg); inhibits the Ang (1-7)-induced decrease in mean arterial pressure (MAP) when administered by microinjection into the nucleus of the solitary tract; has sex-dependent effects on urine flow rate and sodium excretion when AT1 and AT2 receptors are blocked