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Description
Rabbit Anti-Human ABAT polyclonal antibody for WB, IHC. 4-aminobutyrate aminotransferase, mitochondrial, also knwn as, (S)-3-amino-2-methylpropionate transaminase or GABA aminotransferase (GABA-AT) or Gamma-amino-N-butyrate transaminase (GABA transaminase) or GABA-T or L-AIBAT, and encoded by the gene name(s), ABAT or GABAT, is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. Mutations in ABAT have been associated with GABA transaminase deficiency which is an enzymatic deficiency resulting in psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.