Bromodomain Testis-specific Protein (BrdT, domain 257-382 aa), human recombinant
Description
BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. BioVision's recombinant protein includes Bromo 1 domain (257-382 aa) with N-terminal His-tag. MW: 14.9 kDa (126 aa, 257-382 aa + NT His Tag). Purity ≥98%
Size
100 μg
Concentration
n/a
Applications
RUO
Other Names
BrdT, Cancer/testis antigen 9, CT9, RING3-like protein