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Description
Mouse monoclonal antibody specific for human Alpha-Synuclein oligomers only, amino acids EGVVHGVA in b-sheet. Shows good results on paraffin sections.
Immunogen
Amino acid sequence 44-57 TKEGVVHGVATVAE human Alpha-Synuclein
Other Names
Synuclein, Alpha, Alpha-synuclein, Synuclein alpha-140, Non A-beta component of AD amyloid, Non A4 Component Of Amyloid Precursor, NACP, PARK1, PARK4, PD1
An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology. Kovacs GG, Wagner U, Dumont B, Pikkarainen M, Osman AA, Streichenberger N, Leisser I, Verchere J, Baron T, Alafuzoff I, Budka H, Perret-Liaudet A, Lachmann I. Acta Neuropathol. 2012 Jul;124(1):37-50. Rapidly progressive dementia with thalamic degeneration and peculiar cortical prion protein immunoreactivity, but absence of proteinase K resistant PrP: a new disease entity? Kovacs GG, Peden A, Weis S, Hoftberger R, Berghoff AS, Yull H, Strobel T, Koppi S, Katzenschlager R, Langenscheidt D, Assar H, Zaruba E, Groner A, Voigtlander T, Puska G, Hametner E, Grams A, Muigg A, Knoflach M, Laszlo L, Ironside JW, Head MW, Budka H. Acta Neuropathol Commun. 2013 Nov 11;1(1):72.