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Description
Cell proliferation marker: Ki-67/MIB1 has been established as the reference marker for assessing cellular proliferation in tumour cells. The antibody identifies actively dividing cells at all stages of the cell cycle (late G1, S, M and G2 phases), but does not recognize cells in G0 phase. In diagnostic histopathology, Ki-67 has been used as a marker for cell proliferation of solid tumors and some hematological ma-lignancies. A correlation has been demonstrated between Ki-67 index and the histopathological grade of neoplasms.