SMN Tudor Domain (1472-1613 aa) (GST-tagged), Human recombinant
Description
Tudor domains are small protein structural motifs of ~50 amino acids related to the ``Royal family'' of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. The Survival of Motor Neurons (SMN) protein participates in RNA splicing. The Tudor domain of SMN recognizes and binds methylated Sm proteins, which bind small nuclear RNA. SMN is encoded in humans by two separate genes, SMN1 and S
Size
20 μg
Concentration
n/a
Applications
RUO
Other Names
Gemin-1; Component of Gems 1; Survival Motor Neuron Protein