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Description
This antibody detects a 41 kDa protein corresponding to the apparent molecular mass of Atrogin on SDS-PAGE immunoblots of mouse muscle tissue lysates. Similar results were seen in C2C12 cell lysate and the band observed in western blot is specifically blocked by Atrogin-1 peptide (AX2045).
Immunogen
A synthetic peptide (coupled to carrier protein) corresponding to amino acids 23 to 35 in mouse Atrogin. This sequence is highly homologous to human and rat Atrogin (F-box only protein 32).