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Description
This antibody was affinity purified using phospho-β-Catenin (Tyr-333) peptide (without carrier). The antibody detects a 92kDa protein corresponding to the molecular mass of β-Catenin on SDS-PAGE immunoblots of human A431 cells treated with pervanadate, but not in control cells. In addition, the pervanadate induced reactivity is not observed after alkaline phosphatase treatment.
Immunogen
Phospho-β-Catenin (Tyr-333) synthetic peptide (coupled to KLH) that includes amino acid residues around tyrosine 333 of human β-Catenin. This peptide sequence is highly conserved in rat and mouse β-Catenin, and has high homology to the conserved site in γ-Catenin (Tyr-324).