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| Antigenic Specificity | CD41 |
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| Clone | M148 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A purified |
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| Size | 0.1ml |
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| Concentration | 1mg/ml |
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| Applications | Flow cyt, ICC/IF, IHC-Fr, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse anti CD41 [M148]. This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets. |
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| Immunogen | Homogenized human medulloblastoma tissue. |
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| Other Names | CD41; CD41B; GP2B; GPalpha IIb; GPIIb; GTA; HPA3; integrin alpha 2b; Integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITA2B; ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; Platelet membrane glycoprotein IIb; platelet-specific antigen BAK |
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| Gene, Accession # | n/a |
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| Catalog # | IQ643 |
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| Price | |
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| Order / More Info | CD41 Antibody from IMMUQUEST LTD. |
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| Product Specific References | Jones D, et al. A monoclonal antibody binding to human medulloblastoma cells and to the platelet glycoprotein IIB-IIIA complex. Br J Haematol. 1984.57(4):621-31. PMID:6234927 http://www.ncbi.nlm.nih.gov/pubmed/6234927 |
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