An inhibitor of caspase-1 and caspase-3; reduces IL-1β and IL-18 secretion in isolated mouse peritoneal macrophages by cholesterol-treated rPLY at 30 μM; reduces caspase-3 activation by the EGF-like domain of tenascin-C in detached hSMCs in vitro; decreases cell death induced by the EGF-like domain of tenascin-C by 50% at 100 μM; completely inhibits cell death of hSMCs at 200-400 μM
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone|Caspase-1 Inhibitor IV