A selective, cell-active, small molecule inhibitor of SMYD2 (IC50 = 15 nM); inhibits p53 lysine370 monomethylation in KYSE-150 esophageal squamous cell carcinoma cells stably expressing SMYD2 with an IC50 value of 0.6 μM
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
Protein lysine methyltransferase inhibitor probe epigenetics p53 cancer gene regulation biochemical inhibit LLY507 SMYD2 Structural Genomics Consortium SGC