Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 18.7kDa. Partial: 192-325aa. C-terminal 6xHis-Myc-tagged. Hepatitis C virus genotype 1a (isolate 1) (HCV). Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The capsid interacts with HAVCR1 to provide virion attachment to target cell.