Potent and selective SUV420H1/H2 inhibitor (IC50 values are 25 and 144 nM respectively). Exhibits 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. Inhibits the di- and tri-methylation of H4K20me in multiple cell lines (IC50 < 1 μM). To request the negative control for A 196, please fill out the SGC 2043 request form on the SGC website.. Purity 98%. MW (observed): 359.25